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1

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Ha

Journal:

Year:

2013

Language:

english

File:

PDF, 940 KB

english, 2013

2

Genetic Variation in Human DNA Replication Timing

Koren, Amnon, Handsaker, Robert E., Kamitaki, Nolan, Karlić, Rosa, Ghosh, Sulagna, Polak, Paz, Eggan, Kevin, McCarroll, Steven A.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.29 MB

english, 2014

3

Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair

Polak, Paz, Lawrence, Michael S, Haugen, Eric, Stoletzki, Nina, Stojanov, Petar, Thurman, Robert E, Garraway, Levi A, Mirkin, Sergei, Getz, Gad, Stamatoyannopoulos, John A, Sunyaev, Shamil R

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 541 KB

english, 2013

4

Genome-wide patterns and properties of de novo mutations in humans

Francioli, Laurent C, Polak, Paz P, Koren, Amnon, Menelaou, Androniki, Chun, Sung, Renkens, Ivo, van Duijn, Cornelia M, Swertz, Morris, Wijmenga, Cisca, van Ommen, Gertjan, Slagboom, P Eline, Boomsma,

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 2.94 MB

english, 2015

5

Analysis of somatic microsatellite indels identifies driver events in human tumors

Maruvka, Yosef E, Mouw, Kent W, Karlic, Rosa, Parasuraman, Prasanna, Kamburov, Atanas, Polak, Paz, Haradhvala, Nicholas J, Hess, Julian M, Rheinbay, Esther, Brody, Yehuda, Koren, Amnon, Braunstein, Li

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

6

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Getz, Gad, Morris, Quaid, Stein, Linco

Journal:

Nature Communications

Year:

2020

File:

PDF, 808 KB

2020

7

The evolution of transcription-associated biases of mutations across vertebrates

Paz Polak, Robert Querfurth, Peter F Arndt

Journal:

BMC Evolutionary Biology

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

8

Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes

Paz Polak, Eytan Domany

Journal:

Year:

2006

Language:

english

File:

PDF, 477 KB

english, 2006

9

Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

Amnon Koren, Paz Polak, James Nemesh, Jacob J. Michaelson, Jonathan Sebat, Shamil R. Sunyaev, Steven A. McCarroll

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 770 KB

english, 2012

10

Patterns and rates of exonic de novo mutations in autism spectrum disorders

Neale, Benjamin M., Kou, Yan, Liu, Li, Ma’ayan, Avi, Samocha, Kaitlin E., Sabo, Aniko, Lin, Chiao-Feng, Stevens, Christine, Wang, Li-San, Makarov, Vladimir, Polak, Paz, Yoon, Seungtai, Maguire, Jared,

Journal:

Year:

2012

Language:

english

File:

PDF, 317 KB

english, 2012

11

Oscillations and variability in the p53 system

Geva-Zatorsky, Naama, Rosenfeld, Nitzan, Itzkovitz, Shalev, Milo, Ron, Sigal, Alex, Dekel, Erez, Yarnitzky, Talia, Liron, Yuvalal, Polak, Paz, Lahav, Galit, Alon, Uri

Journal:

Molecular Systems Biology

Year:

2006

Language:

english

File:

PDF, 367 KB

english, 2006

12

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

Polak, Paz, Karlić, Rosa, Koren, Amnon, Thurman, Robert, Sandstrom, Richard, Lawrence, Michael S., Reynolds, Alex, Rynes, Eric, Vlahoviček, Kristian, Stamatoyannopoulos, John A., Sunyaev, Shamil R.

Journal:

Year:

2015

Language:

english

File:

PDF, 6.55 MB

english, 2015

13

The Lazy Travelling Salesman Problem in $\mathbb{R}^2$

Polak, Paz, Wolansky, Gershon

Journal:

ESAIM Control Optimisation and Calculus of Variations

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

14

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

Haradhvala, Nicholas J., Polak, Paz, Stojanov, Petar, Covington, Kyle R., Shinbrot, Eve, Hess, Julian M., Rheinbay, Esther, Kim, Jaegil, Maruvka, Yosef E., Braunstein, Lior Z., Kamburov, Atanas, Hanaw

Journal:

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

15

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

Kim, Jaegil, Mouw, Kent W, Polak, Paz, Braunstein, Lior Z, Kamburov, Atanas, Tiao, Grace, Kwiatkowski, David J, Rosenberg, Jonathan E, Van Allen, Eliezer M, D'Andrea, Alan D, Getz, Gad

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 2.03 MB

english, 2016

16

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

Kazanov, Marat D., Roberts, Steven A., Polak, Paz, Stamatoyannopoulos, John, Klimczak, Leszek J., Gordenin, Dmitry A., Sunyaev, Shamil R.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.00 MB

english, 2015

17

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

Polak, Paz, Kim, Jaegil, Braunstein, Lior Z, Karlic, Rosa, Haradhavala, Nicholas J, Tiao, Grace, Rosebrock, Daniel, Livitz, Dimitri, Kübler, Kirsten, Mouw, Kent W, Kamburov, Atanas, Maruvka, Yosef E,

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 16.44 MB

english, 2017

18

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations

Wardell, Christopher P., Fujita, Masashi, Yamada, Toru, Simbolo, Michele, Fassan, Matteo, Karlic, Rosa, Polak, Paz, Kim, Jaegil, Hatanaka, Yutaka, Maejima, Kazuhiro, Lawlor, Rita T., Nakanishi, Yoshit

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

19

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma

Gopal, Raj K., Kübler, Kirsten, Calvo, Sarah E., Polak, Paz, Livitz, Dimitri, Rosebrock, Daniel, Sadow, Peter M., Campbell, Braidie, Donovan, Samuel E., Amin, Salma, Gigliotti, Benjamin J., Grabarek,

Journal:

Year:

2018

Language:

english

File:

PDF, 2.77 MB

english, 2018

20

Indirect Bactericidal Properties of Recombinant Human Bone Morphogenetic Protein 2 In Vitro

Cohen, Adir, Polak, David, Nir-Paz, Ran, Westreich, Neetzan, Casap, Nardi

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2019

File:

PDF, 1.27 MB

2019

21

Indirect Bactericidal Properties of Recombinant Human Bone Morphogenetic Protein 2 In Vitro

Cohen, Adir, Polak, David, Nir-Paz, Ran, Westreich, Neetzan, Casap, Nardi

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2019

Language:

english

File:

PDF, 1.27 MB

english, 2019

22

Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients in New York City

Sigel, Keith, Swartz, Talia, Golden, Eddye, Paranjpe, Ishan, Somani, Sulaiman, Richter, Felix, De Freitas, Jessica K, Miotto, Riccardo, Zhao, Shan, Polak, Paz, Mutetwa, Tinaye, Factor, Stephanie, Meha

Journal:

Clinical Infectious Diseases

Year:

2020

File:

PDF, 800 KB

2020

23

Genomic Profiling of Prostate Cancers from Men with African and European Ancestry

Koga, Yusuke, Song, Hanbing, Chalmers, Zachary R., Newberg, Justin, Kim, Eejung, Carrot-Zhang, Jian, Piou, Daphnee, Polak, Paz, Abdulkadir, Sarki A., Ziv, Elad, Meyerson, Matthew, Frampton, Garrett M.

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 748 KB

2020

24

Bilateral Tumors â Inherited or Acquired?

Phimister, Elizabeth G., Foulkes, William D., Polak, Paz

Journal:

New England Journal of Medicine

Year:

2020

File:

PDF, 482 KB

2020

25

Etiologic Index â A Case-Only Measure of BRCA1/2 âAssociated Cancer Risk

Hughley, Raymond, Karlic, Rosa, Joshi, Himanshu, Turnbull, Clare, Foulkes, William D., Polak, Paz

Journal:

New England Journal of Medicine

Year:

2020

File:

PDF, 398 KB

2020